bmpr 1b gene Search Results


gene exp bmpr1b hs01010965 m1  (Thermo Fisher)
94
Thermo Fisher gene exp bmpr1b hs01010965 m1
a Volcano plot showing differential gene expression (two-tailed DESeq2’s Wald test, P adj <0.05) of HCFs in response to EF-1 ( n = 3 biological replicates). The horizontal dashed line indicates -Log10 ( P adj <0.05). b Heatmap showing log2 fold change estimates for top DEGs in EF-1-treated HCFs relative to the control group. c Venn diagram of overlapping DEGs between the NRG1 and EF-1 group. d Heatmap showing log2 fold change estimates for top DEGs in EF-1- or NRG1-treated HCFs relative to the control group. e GSEA of HCFs with EF - 1 or NRG1 for gene signatures of TGF-β, PI3K/Akt and MAPK pathway-regulated genes. P -values were adjusted via the Benjamini–Hochberg procedure. f – h RT-qPCR on signaling pathway genes in HCFs; normalized FC compared to vehicle ( n = 4 biological replicates for every value in each group): f ID2 and <t>BMPR1B</t> , genes involved in TGFβ signaling, g CACNA2D4 and DUSP2 , genes involved in MAPK/ERK signaling and h NR4A1 and SGK1 , genes involved in PI3k-Akt signaling. All data are represented as mean ± SD, one-way ANOVA with Tukey’s multiple comparisons test. Source data are provided as a Source Data file. Akt protein kinase B, ANOVA analysis of variance, BMPR1B bone morphogenetic protein receptor type 1B, CACNA2D4 calcium voltage-gated channel auxiliary subunit alpha-2 delta-4, DEG differentially expressed gene, DUSP2 dual specificity phosphatase 2, ERK extracellular signal-regulated kinase, FC fold change, GSEA gene set enrichment analysis, HCF human cardiac fibroblast, ID2 Inhibitor of DNA Binding 2, MAPK mitogen-activated protein kinase, NES normalized enrichment score, NRG1 neuregulin-1, NR4A1 nuclear receptor subfamily 4 group A member 1, PI3K phosphatidylinositol 3-kinase, RT-qPCR real-time quantitative polymerase chain reaction, SGK1 serum/glucocorticoid-regulated kinase 1, TGF-β transforming growth factor-β.
Gene Exp Bmpr1b Hs01010965 M1, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/bmpr+1b+gene/pmc11724075-432-19-6?v=Thermo+Fisher
Average 94 stars, based on 1 article reviews
gene exp bmpr1b hs01010965 m1 - by Bioz Stars, 2026-08
94/100 stars
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bmpr 1b gene  (Jena Bioscience)
90
Jena Bioscience bmpr 1b gene
a Volcano plot showing differential gene expression (two-tailed DESeq2’s Wald test, P adj <0.05) of HCFs in response to EF-1 ( n = 3 biological replicates). The horizontal dashed line indicates -Log10 ( P adj <0.05). b Heatmap showing log2 fold change estimates for top DEGs in EF-1-treated HCFs relative to the control group. c Venn diagram of overlapping DEGs between the NRG1 and EF-1 group. d Heatmap showing log2 fold change estimates for top DEGs in EF-1- or NRG1-treated HCFs relative to the control group. e GSEA of HCFs with EF - 1 or NRG1 for gene signatures of TGF-β, PI3K/Akt and MAPK pathway-regulated genes. P -values were adjusted via the Benjamini–Hochberg procedure. f – h RT-qPCR on signaling pathway genes in HCFs; normalized FC compared to vehicle ( n = 4 biological replicates for every value in each group): f ID2 and <t>BMPR1B</t> , genes involved in TGFβ signaling, g CACNA2D4 and DUSP2 , genes involved in MAPK/ERK signaling and h NR4A1 and SGK1 , genes involved in PI3k-Akt signaling. All data are represented as mean ± SD, one-way ANOVA with Tukey’s multiple comparisons test. Source data are provided as a Source Data file. Akt protein kinase B, ANOVA analysis of variance, BMPR1B bone morphogenetic protein receptor type 1B, CACNA2D4 calcium voltage-gated channel auxiliary subunit alpha-2 delta-4, DEG differentially expressed gene, DUSP2 dual specificity phosphatase 2, ERK extracellular signal-regulated kinase, FC fold change, GSEA gene set enrichment analysis, HCF human cardiac fibroblast, ID2 Inhibitor of DNA Binding 2, MAPK mitogen-activated protein kinase, NES normalized enrichment score, NRG1 neuregulin-1, NR4A1 nuclear receptor subfamily 4 group A member 1, PI3K phosphatidylinositol 3-kinase, RT-qPCR real-time quantitative polymerase chain reaction, SGK1 serum/glucocorticoid-regulated kinase 1, TGF-β transforming growth factor-β.
Bmpr 1b Gene, supplied by Jena Bioscience, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/bmpr+1b+gene/pmc07160958-29-4-10?v=Jena+Bioscience
Average 90 stars, based on 1 article reviews
bmpr 1b gene - by Bioz Stars, 2026-08
90/100 stars
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gene exp kdr hs00911700 m1  (Thermo Fisher)
99
Thermo Fisher gene exp kdr hs00911700 m1
a Volcano plot showing differential gene expression (two-tailed DESeq2’s Wald test, P adj <0.05) of HCFs in response to EF-1 ( n = 3 biological replicates). The horizontal dashed line indicates -Log10 ( P adj <0.05). b Heatmap showing log2 fold change estimates for top DEGs in EF-1-treated HCFs relative to the control group. c Venn diagram of overlapping DEGs between the NRG1 and EF-1 group. d Heatmap showing log2 fold change estimates for top DEGs in EF-1- or NRG1-treated HCFs relative to the control group. e GSEA of HCFs with EF - 1 or NRG1 for gene signatures of TGF-β, PI3K/Akt and MAPK pathway-regulated genes. P -values were adjusted via the Benjamini–Hochberg procedure. f – h RT-qPCR on signaling pathway genes in HCFs; normalized FC compared to vehicle ( n = 4 biological replicates for every value in each group): f ID2 and <t>BMPR1B</t> , genes involved in TGFβ signaling, g CACNA2D4 and DUSP2 , genes involved in MAPK/ERK signaling and h NR4A1 and SGK1 , genes involved in PI3k-Akt signaling. All data are represented as mean ± SD, one-way ANOVA with Tukey’s multiple comparisons test. Source data are provided as a Source Data file. Akt protein kinase B, ANOVA analysis of variance, BMPR1B bone morphogenetic protein receptor type 1B, CACNA2D4 calcium voltage-gated channel auxiliary subunit alpha-2 delta-4, DEG differentially expressed gene, DUSP2 dual specificity phosphatase 2, ERK extracellular signal-regulated kinase, FC fold change, GSEA gene set enrichment analysis, HCF human cardiac fibroblast, ID2 Inhibitor of DNA Binding 2, MAPK mitogen-activated protein kinase, NES normalized enrichment score, NRG1 neuregulin-1, NR4A1 nuclear receptor subfamily 4 group A member 1, PI3K phosphatidylinositol 3-kinase, RT-qPCR real-time quantitative polymerase chain reaction, SGK1 serum/glucocorticoid-regulated kinase 1, TGF-β transforming growth factor-β.
Gene Exp Kdr Hs00911700 M1, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/bmpr+1b+gene/pmc11181359__BLOOD_BLD___2023___021777___mmc1-80-42--1?v=Thermo+Fisher
Average 99 stars, based on 1 article reviews
gene exp kdr hs00911700 m1 - by Bioz Stars, 2026-08
99/100 stars
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gene exp bmpr1b mm00432117 m1  (Thermo Fisher)
88
Thermo Fisher gene exp bmpr1b mm00432117 m1
a Volcano plot showing differential gene expression (two-tailed DESeq2’s Wald test, P adj <0.05) of HCFs in response to EF-1 ( n = 3 biological replicates). The horizontal dashed line indicates -Log10 ( P adj <0.05). b Heatmap showing log2 fold change estimates for top DEGs in EF-1-treated HCFs relative to the control group. c Venn diagram of overlapping DEGs between the NRG1 and EF-1 group. d Heatmap showing log2 fold change estimates for top DEGs in EF-1- or NRG1-treated HCFs relative to the control group. e GSEA of HCFs with EF - 1 or NRG1 for gene signatures of TGF-β, PI3K/Akt and MAPK pathway-regulated genes. P -values were adjusted via the Benjamini–Hochberg procedure. f – h RT-qPCR on signaling pathway genes in HCFs; normalized FC compared to vehicle ( n = 4 biological replicates for every value in each group): f ID2 and <t>BMPR1B</t> , genes involved in TGFβ signaling, g CACNA2D4 and DUSP2 , genes involved in MAPK/ERK signaling and h NR4A1 and SGK1 , genes involved in PI3k-Akt signaling. All data are represented as mean ± SD, one-way ANOVA with Tukey’s multiple comparisons test. Source data are provided as a Source Data file. Akt protein kinase B, ANOVA analysis of variance, BMPR1B bone morphogenetic protein receptor type 1B, CACNA2D4 calcium voltage-gated channel auxiliary subunit alpha-2 delta-4, DEG differentially expressed gene, DUSP2 dual specificity phosphatase 2, ERK extracellular signal-regulated kinase, FC fold change, GSEA gene set enrichment analysis, HCF human cardiac fibroblast, ID2 Inhibitor of DNA Binding 2, MAPK mitogen-activated protein kinase, NES normalized enrichment score, NRG1 neuregulin-1, NR4A1 nuclear receptor subfamily 4 group A member 1, PI3K phosphatidylinositol 3-kinase, RT-qPCR real-time quantitative polymerase chain reaction, SGK1 serum/glucocorticoid-regulated kinase 1, TGF-β transforming growth factor-β.
Gene Exp Bmpr1b Mm00432117 M1, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 88/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/bmpr+1b+gene/pm35545056-352-69--1?v=Thermo+Fisher
Average 88 stars, based on 1 article reviews
gene exp bmpr1b mm00432117 m1 - by Bioz Stars, 2026-08
88/100 stars
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gene exp acvr1b mm00475713 m1  (Thermo Fisher)
91
Thermo Fisher gene exp acvr1b mm00475713 m1
a Volcano plot showing differential gene expression (two-tailed DESeq2’s Wald test, P adj <0.05) of HCFs in response to EF-1 ( n = 3 biological replicates). The horizontal dashed line indicates -Log10 ( P adj <0.05). b Heatmap showing log2 fold change estimates for top DEGs in EF-1-treated HCFs relative to the control group. c Venn diagram of overlapping DEGs between the NRG1 and EF-1 group. d Heatmap showing log2 fold change estimates for top DEGs in EF-1- or NRG1-treated HCFs relative to the control group. e GSEA of HCFs with EF - 1 or NRG1 for gene signatures of TGF-β, PI3K/Akt and MAPK pathway-regulated genes. P -values were adjusted via the Benjamini–Hochberg procedure. f – h RT-qPCR on signaling pathway genes in HCFs; normalized FC compared to vehicle ( n = 4 biological replicates for every value in each group): f ID2 and <t>BMPR1B</t> , genes involved in TGFβ signaling, g CACNA2D4 and DUSP2 , genes involved in MAPK/ERK signaling and h NR4A1 and SGK1 , genes involved in PI3k-Akt signaling. All data are represented as mean ± SD, one-way ANOVA with Tukey’s multiple comparisons test. Source data are provided as a Source Data file. Akt protein kinase B, ANOVA analysis of variance, BMPR1B bone morphogenetic protein receptor type 1B, CACNA2D4 calcium voltage-gated channel auxiliary subunit alpha-2 delta-4, DEG differentially expressed gene, DUSP2 dual specificity phosphatase 2, ERK extracellular signal-regulated kinase, FC fold change, GSEA gene set enrichment analysis, HCF human cardiac fibroblast, ID2 Inhibitor of DNA Binding 2, MAPK mitogen-activated protein kinase, NES normalized enrichment score, NRG1 neuregulin-1, NR4A1 nuclear receptor subfamily 4 group A member 1, PI3K phosphatidylinositol 3-kinase, RT-qPCR real-time quantitative polymerase chain reaction, SGK1 serum/glucocorticoid-regulated kinase 1, TGF-β transforming growth factor-β.
Gene Exp Acvr1b Mm00475713 M1, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/bmpr+1b+gene/pm30654712-120-28-52?v=Thermo+Fisher
Average 91 stars, based on 1 article reviews
gene exp acvr1b mm00475713 m1 - by Bioz Stars, 2026-08
91/100 stars
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gene exp bmpr1b hs01010966 m1  (Thermo Fisher)
86
Thermo Fisher gene exp bmpr1b hs01010966 m1
a Volcano plot showing differential gene expression (two-tailed DESeq2’s Wald test, P adj <0.05) of HCFs in response to EF-1 ( n = 3 biological replicates). The horizontal dashed line indicates -Log10 ( P adj <0.05). b Heatmap showing log2 fold change estimates for top DEGs in EF-1-treated HCFs relative to the control group. c Venn diagram of overlapping DEGs between the NRG1 and EF-1 group. d Heatmap showing log2 fold change estimates for top DEGs in EF-1- or NRG1-treated HCFs relative to the control group. e GSEA of HCFs with EF - 1 or NRG1 for gene signatures of TGF-β, PI3K/Akt and MAPK pathway-regulated genes. P -values were adjusted via the Benjamini–Hochberg procedure. f – h RT-qPCR on signaling pathway genes in HCFs; normalized FC compared to vehicle ( n = 4 biological replicates for every value in each group): f ID2 and <t>BMPR1B</t> , genes involved in TGFβ signaling, g CACNA2D4 and DUSP2 , genes involved in MAPK/ERK signaling and h NR4A1 and SGK1 , genes involved in PI3k-Akt signaling. All data are represented as mean ± SD, one-way ANOVA with Tukey’s multiple comparisons test. Source data are provided as a Source Data file. Akt protein kinase B, ANOVA analysis of variance, BMPR1B bone morphogenetic protein receptor type 1B, CACNA2D4 calcium voltage-gated channel auxiliary subunit alpha-2 delta-4, DEG differentially expressed gene, DUSP2 dual specificity phosphatase 2, ERK extracellular signal-regulated kinase, FC fold change, GSEA gene set enrichment analysis, HCF human cardiac fibroblast, ID2 Inhibitor of DNA Binding 2, MAPK mitogen-activated protein kinase, NES normalized enrichment score, NRG1 neuregulin-1, NR4A1 nuclear receptor subfamily 4 group A member 1, PI3K phosphatidylinositol 3-kinase, RT-qPCR real-time quantitative polymerase chain reaction, SGK1 serum/glucocorticoid-regulated kinase 1, TGF-β transforming growth factor-β.
Gene Exp Bmpr1b Hs01010966 M1, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/bmpr+1b+gene/pm18985480-64-46-18?v=Thermo+Fisher
Average 86 stars, based on 1 article reviews
gene exp bmpr1b hs01010966 m1 - by Bioz Stars, 2026-08
86/100 stars
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wdr5 polyclonal antibody  (Elabscience)
N/A
This gene encodes a member of the WD repeat protein family WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly his and trp asp GH WD which may facilitate
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human bmp-3b/gdf-10 gene orf cdna clone in cloning vector  (Sino Biological)
N/A
Full length Clone DNA of Human growth differentiation factor 10.
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gdf-11/bmp-11 recombinant protein antigen  (Novus Biologicals)
N/A
GDF-11/BMP-11 Recombinant Protein Antigen
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rat bmp-3b/gdf-10 gene orf cdna clone expression plasmid, n-ha tag  (Sino Biological)
N/A
Full length Clone DNA of Rat growth differentiation factor 10 with N terminal HA tag.
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bone morphogenetic protein receptor-1b human recombinant  (Angio-Proteomie)
N/A
BMPR1B Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 136 amino acids (14-126 a.a) and having a molecular mass of 15.1kDa. BMPR1B is fused to a 23 amino acid His-tag at
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bmpr1b human qpcr template standard  (OriGene)
N/A
qPCR primer pairs and template standards against Homo sapiens gene BMPR1B
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Image Search Results


a Volcano plot showing differential gene expression (two-tailed DESeq2’s Wald test, P adj <0.05) of HCFs in response to EF-1 ( n = 3 biological replicates). The horizontal dashed line indicates -Log10 ( P adj <0.05). b Heatmap showing log2 fold change estimates for top DEGs in EF-1-treated HCFs relative to the control group. c Venn diagram of overlapping DEGs between the NRG1 and EF-1 group. d Heatmap showing log2 fold change estimates for top DEGs in EF-1- or NRG1-treated HCFs relative to the control group. e GSEA of HCFs with EF - 1 or NRG1 for gene signatures of TGF-β, PI3K/Akt and MAPK pathway-regulated genes. P -values were adjusted via the Benjamini–Hochberg procedure. f – h RT-qPCR on signaling pathway genes in HCFs; normalized FC compared to vehicle ( n = 4 biological replicates for every value in each group): f ID2 and BMPR1B , genes involved in TGFβ signaling, g CACNA2D4 and DUSP2 , genes involved in MAPK/ERK signaling and h NR4A1 and SGK1 , genes involved in PI3k-Akt signaling. All data are represented as mean ± SD, one-way ANOVA with Tukey’s multiple comparisons test. Source data are provided as a Source Data file. Akt protein kinase B, ANOVA analysis of variance, BMPR1B bone morphogenetic protein receptor type 1B, CACNA2D4 calcium voltage-gated channel auxiliary subunit alpha-2 delta-4, DEG differentially expressed gene, DUSP2 dual specificity phosphatase 2, ERK extracellular signal-regulated kinase, FC fold change, GSEA gene set enrichment analysis, HCF human cardiac fibroblast, ID2 Inhibitor of DNA Binding 2, MAPK mitogen-activated protein kinase, NES normalized enrichment score, NRG1 neuregulin-1, NR4A1 nuclear receptor subfamily 4 group A member 1, PI3K phosphatidylinositol 3-kinase, RT-qPCR real-time quantitative polymerase chain reaction, SGK1 serum/glucocorticoid-regulated kinase 1, TGF-β transforming growth factor-β.

Journal: Nature Communications

Article Title: Small-molecule-induced ERBB4 activation to treat heart failure

doi: 10.1038/s41467-024-54908-5

Figure Lengend Snippet: a Volcano plot showing differential gene expression (two-tailed DESeq2’s Wald test, P adj <0.05) of HCFs in response to EF-1 ( n = 3 biological replicates). The horizontal dashed line indicates -Log10 ( P adj <0.05). b Heatmap showing log2 fold change estimates for top DEGs in EF-1-treated HCFs relative to the control group. c Venn diagram of overlapping DEGs between the NRG1 and EF-1 group. d Heatmap showing log2 fold change estimates for top DEGs in EF-1- or NRG1-treated HCFs relative to the control group. e GSEA of HCFs with EF - 1 or NRG1 for gene signatures of TGF-β, PI3K/Akt and MAPK pathway-regulated genes. P -values were adjusted via the Benjamini–Hochberg procedure. f – h RT-qPCR on signaling pathway genes in HCFs; normalized FC compared to vehicle ( n = 4 biological replicates for every value in each group): f ID2 and BMPR1B , genes involved in TGFβ signaling, g CACNA2D4 and DUSP2 , genes involved in MAPK/ERK signaling and h NR4A1 and SGK1 , genes involved in PI3k-Akt signaling. All data are represented as mean ± SD, one-way ANOVA with Tukey’s multiple comparisons test. Source data are provided as a Source Data file. Akt protein kinase B, ANOVA analysis of variance, BMPR1B bone morphogenetic protein receptor type 1B, CACNA2D4 calcium voltage-gated channel auxiliary subunit alpha-2 delta-4, DEG differentially expressed gene, DUSP2 dual specificity phosphatase 2, ERK extracellular signal-regulated kinase, FC fold change, GSEA gene set enrichment analysis, HCF human cardiac fibroblast, ID2 Inhibitor of DNA Binding 2, MAPK mitogen-activated protein kinase, NES normalized enrichment score, NRG1 neuregulin-1, NR4A1 nuclear receptor subfamily 4 group A member 1, PI3K phosphatidylinositol 3-kinase, RT-qPCR real-time quantitative polymerase chain reaction, SGK1 serum/glucocorticoid-regulated kinase 1, TGF-β transforming growth factor-β.

Article Snippet: The following TaqMan primers were used (Thermo Fisher Scientific): GAPDH (Hs02758991_g1, Mm99999915_g1 and Rn01775763_g1), PGK1 (Hs99999906_m1), ID2 (Hs04187239_m1), BMPR1B (Hs01010965_m1), CACNA2D4 (Hs00297782_m1), DUSP2 (Hs00358879_m1), NR4A1 (Hs00374226_m1), SGK1 (Hs00178612_m1), COL1A1 (Mm00801666_g1), COL3A1 (Hs00943809_m1 and Mm00802305_g1), ERBB4 (Hs00955525_m1 and Rn00572447_m1), ACTB (Mm02619580_g1) and ANP (Mm01255747_g1).

Techniques: Gene Expression, Two Tailed Test, Control, Quantitative RT-PCR, Binding Assay, Real-time Polymerase Chain Reaction